Sylvie Girard

Title: Associate research professor (accredited)
Département d’obstétrique-gynécologie
Address: Centre de recherche du CHU Sainte-Justine
3175, chemin Côte-Sainte-Catherine
Montréal (Québec)
H3T 1C5
Room: Office: A715
Labo: 1725
Phone: Office: 514-345-4931 ext. 2448
Labo: 514-345-4931 ext. 4133
Email: sylvie.girard@umontreal.ca

Biography

Dr. Sylvie Girard completed her Ph.D. in Immunology at the Université de Sherbrooke, working on perinatal inflammatory processes and their impact on brain development in the newborn. She then pursued post-doctoral studies at the University of Manchester in the United Kingdom and then at Yale University in the United States where she acquired expertise in reproductive immunology. Dr. Girard joined the Department of Obstetrics and Gynecology at the Université de Montréal in 2014 and focuses on inflammatory mechanisms at the materno-fetal interface in both humans and animals and the effects on the development of the newborn. She is now accredited with the Department of microbiology, infectiology and immunology at the Université de Montréal since 2015.

Team

  • Marie-Ève Brien (étudiante au doctorat)
  • Cyntia Duval (étudiante au doctorat)
  • Virginie Gaudreault (étudiante à la maitrise)
  • Ines Boufaied (assistante de recherche)

Themes

  • Inflammation
  • Immune activation
  • Immunology of reproduction
  • Child development

Research topics

  • Inflammation during pregnancy
  • Preeclampsia
  • Prematurity
  • Placenta
  • Fetal brain

Publications

  • Brien ME, Duval C, Palacios J, Boufaied I, Hudon-Thibeault AA, Nadeau-Vallee M, Vaillancourt C, Sibley CP, Abrahams VM, Jones RL, Girard S*. Uric acid crystals induce placental inflammation and alter trophoblast function via an IL-1-dependent pathway: implication for fetal growth restriction. Journal of Immunology, 2017; 198(1): 443-451.
  • Nadeau-Vallee M, Obari D, Palacios J, Brien ME, Duval C, Chemtob S, Girard S*. Sterile inflammation and pregnancy complications: a review. Reproduction, 2016; 152(6): R277-292.
  • Girard S, Heazell AEP, Derricott H, Allan SM, Sibley CP, Abrahams VM, Jones RL. Circulating cytokines and alarmins associated with placental inflammation in high-risk pregnancies. American Journal of Reproductive Immunology, 2014; 72(4):422-434.
  • Girard S, Tremblay L, Lepage M, Sébire G. IL-1 receptor antagonist protects against placental and neurodevelopmental defects induced by maternal inflammation. Journal of Immunology, 2010; 184(7): 3997-4005