Isabel Fernandez

Biography

To come up

Team 

To come up

Theme

• Immunology
• Immunodeficiency

Research topics

• Inborn immunity and infections
• Molecular mechanisms in immune deficient patients
• Characterization of  pathophysiologic mecanisms in immunodeficiencies.

Publications

• Labrosse R, Abou-Diab J, Blincoe A, Cros G, Luu TM, Deslandres C, Dirks M, Fazilleau L , Ovetchkine P, Teira P, LeDeist F, Fernandez I, Touzot F, Decaluwe H, Halac U and Haddad E. Very Early-Onset Inflammatory Manifestations of X-Linked Chronic Granulomatous Disease. Front Immunol 8: 1167é 2017.
• Fernandez I, Patey N, Marchand V, Birlea M, Maranda B, Haddad E, Decaluwe H, Le Deist F. Multiple intestinal atresia with combined immune deficiency related to TTC7A defect is a multiorgan pathology: study of a French-Canadian-based cohort. Medicine (Baltimore) 93:e327, 2014.
• Fernandez I, Brito RM, Bidet P, Rallu F, Laferrière C, Ovetchkine P, Le Deist F. Invasive group A Streptococcus disease in French-Canadian children is not associated with a defect in MyD88/IRAK4-pathway. Allergy Asthma Clin Immunol 10:9, 2014.
• Picard M, Fernandez MI, Des Roches A, Bégin P, Paradis J, Paradis L, Le Deist F. Ceftazidime-induced drug reaction with eosinophilia and systemic symptoms (DRESS) complicated by hemophagocytic lymphohistiocytosis. J Allergy Clin Immunol Pract. 1:409-412, 2013.
• Samuels ME, Majewski J, Alirezaie N, Fernandez I, Casals F, Patey N, Decaluwe H, Gosselin I, Haddad E, Hodgkinson A, Idaghdour Y, Marchand V, Michaud JL, Rodrigue MA, Desjardins S, Dubois S, Le Deist F, Awadalla P, Raymond V, Maranda B. Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia. J Med Genet 50:324-329, 2013.
• Fernandez MI, Heuzé ML, Martinez-Cingolani C, Volpe E, Donnadieu MH, Piel M, Homey B, Lennon-Duménil AM, Soumelis V. The human cytokine TSLP triggers a cell autonomous dendritic cell migration in confined environments. Blood, 118: 3862-3869, 2011.