Johanne Poudrier

Biography

Dr. Poudrier graduated from the Université de Montréal (M.Sc., supervisors Dr. Pelletier and Dr. Montplaisir) and at McGill University (PhD, supervisor Dr. Owens). She pursued her postdoctoral studies in immunology, first in London at the Royal Postgraduate Medical School (RPMS) with Dr. Gray, and then in Geneva at the Geneva Biomedical Research Institute, later Serono, with Dr. Kosco-Vilbois. After a 6-year research associate with Dr. Jolicoeur at the Montreal Institute of Clinical Research (IRCM), Dr. Poudrier joined Dr. Roger’s team at the CHUM Research Center. She began her academic career in the Department of Microbiology, Infectiology and Immunology at the Université de Montréal, where she is now an Associate Clinical Professor. She is the author of more than 40 publications dealing mainly with dendritic cells and B lymphocytes, both on murine models and on human specimens.

Team

• Works with Dr. Michel Roger and team

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Themes

• Immunology
• Virology

Research topics

• Dendritic cells and B lymphocytes in the context of control/resistance vs progression of HIV infection
• Impact of B lymphocyte stimulator (BLyS)/BAFF

Publications

• Fourcade L, Sabourin-Poirier C, Perraud V, Faucher MC, Chagnon-Choquet J, Labbé AC, Alary M, Guédou F, Poudrier J, Roger M. Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c+ B-cells in the genital tract. PLoS Pathog. 2019 Jun 7;15(6):e1007840. doi: 10.1371/journal.ppat.1007840. PMID: 31173604; PMCID: PMC6583986.
• Doyon-Laliberté K, Chagnon-Choquet J, Byrns M, Aranguren M, Memmi M, Chrobak P, Stagg J, Poudrier J, Roger M. NR4A Expression by Human Marginal Zone B-Cells. Antibodies (Basel). 2019 Oct 11;8(4):50. doi: 10.3390/antib8040050. PMID: 31614541; PMCID: PMC6963983.
• Fourcade L, Poudrier J, Roger M. Natural Immunity to HIV: A Template for Vaccine Strategies. Viruses. 2018 Apr 23;10(4):215. doi: 10.3390/v10040215. PMID: 29690575; PMCID: PMC5923509.
• Sabourin-Poirier, L. Fourcade, J. Chagnon-Choquet, A-C. Labbé, M. Alary, F. Guédou, J. Poudrier*, and M. Roger* Blood B Lymphocyte Stimulator (BLyS)/BAFF levels may reflect natural immunity to HIV in highly exposed uninfected Beninese Commercial Sex Workers. Scientific Reports 2016 Aug26; 6:32318. doi: 10.1038/srep32318. *correspondence; co-seniorship
• Fontaine, Chagnon-Choquet J, Valcke HS, J. Poudrier* and M.Roger*; Montreal Primary HIV Infection and Long-Term Non-Progressor Study Groups. High expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans. Blood. 2011 Jan 6; 117(1):145-55. Epub 2010 Sep 24. *correspondence; co-seniorship