{"id":7527,"date":"2014-07-31T14:06:01","date_gmt":"2014-07-31T14:06:01","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/andres-finzi\/"},"modified":"2023-12-20T15:48:11","modified_gmt":"2023-12-20T14:48:11","slug":"andres-finzi","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/andres-finzi\/","title":{"rendered":"Andr\u00e9s Finzi"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/2023\/12\/Capture-decran-2023-12-19-144133.jpg\" alt=\"\" width=\"227\" height=\"190\" class=\"alignnone size-full wp-image-16401\" \/><\/p>\n<p><\/div>\n<table style=\"width: 378px\">\n<tbody>\n<tr>\n<td style=\"width: 83px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 294px\">Full Professor<br \/>\nCanada Research Chair in retroviral entry<strong>\u00a0<\/strong>Member of The College of the Royal Society of Canada<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 83px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 294px\">Centre de recherche du CHUM (CRCHUM)<br \/>\n900, rue St-Denis, Tour Viger<br \/>\nMontr\u00e9al, Qu\u00e9bec, Canada<br \/>\nH2X 0A9<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 83px\"><strong>Room:<\/strong><\/td>\n<td style=\"width: 294px\">Office: R09-420<br \/>\nLabo: R09.300<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 83px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 294px\">Office: 514-890-8000 ext: 35264<br \/>\nLabo: 514-890-8000 ext: 31248<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 83px\"><strong>Fax:<\/strong><\/td>\n<td style=\"width: 294px\">514-412-7377<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 83px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 294px\"><a href=\"mailto:andres.finzi@umontreal.ca\">andres.finzi@umontreal.ca<\/a><br \/>\n<a href=\"mailto:andres.finzi@gmail.com\">andres.finzi@gmail.com<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<hr\/>\n<h2 style=\"text-align: justify\"><strong>Biography<\/strong><\/h2>\n<p style=\"text-align: justify\">Dr. Finzi graduated from the Universit\u00e9 de Montr\u00e9al. He continues his postgraduate studies in virology in Dr. Joseph Sodroski&#8217;s laboratory at the Dana-Farber Cancer Institute (Harvard Medical School) where he identifies key structural elements within HIV-1 envelope glycoproteins essential for viral entry. This discovery earned him the prestigious Mathilde Krim Scholarship, awarded by the American Society for AIDS Research (amfAR). Dr. Finzi began an academic career in the Department of Microbiology, Infectiology and Immunology at the Universit\u00e9 de Montr\u00e9al in September 2011, and received funding from the Bill and Melinda Gates Foundation and the Canadian Foundation for Innovation (CFI), The Canadian Institutes of Health Research (CIHR), National Institutes of Health (NIH) and the Quebec Health Research Fund (FRQS). Since 2014, Dr. Finzi has been awarded a Canada Research Chair in retroviral entry Dr Finzi made several seminal contributions to the field of HIV\/AIDS and SARS-CoV-2 research. His work has important implications for the development of new therapeutic strategies to fight HIV-1 and SARS-CoV-2.\u00a0\u00a0 His work earned him several prestigious awards, including the Young Faculty Award bestowed by the NIH Center for HIV\/AIDS Vaccine and Immunogen Design (CHAVI-ID, 2016), the Joe Doupe Young Investigator Award (Canadian Society for Clinical Investigation, 2019), the Andr\u00e9 Dupont Young Investigator Award (Club de recherches cliniques du Qu\u00e9bec, 2020), \u00c9toile Effervescence by Montr\u00e9al INVIVO (2022). The quality and impact of his research was recognized by his admission to the College of New Scholars, Artists and Scientists of the Royal Society of Canada in 2020. F<\/p>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Team<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>\u00c9tienne B\u00e9langer (MSc student)<\/li>\n<li>Katrina Dionne (MSc student)<\/li>\n<li>Guillaume Beaudoin-Bussi\u00e8res (PhD student)<\/li>\n<li>Lorie Marchitto (PhD student)<\/li>\n<li>Mehdi Benlarbi (PhD student)<\/li>\n<li>Manon Nayrac (postdoctoral fellow)<\/li>\n<li>Alexandra Tauzin (postdoctoral fellow)<\/li>\n<li>Kaho Matsumoto (postdoctoral fellow)<\/li>\n<li>Shilei Ding (research associate)<\/li>\n<li>Jonathan Richard (research associate)<\/li>\n<li>Catherine Bourassa (technicien)<\/li>\n<li>Debashree Chatterjee (research coordinator)<\/li>\n<li>Halima Medjahed (research assistant)<\/li>\n<li><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Themes<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Virology (HIV, SARS-CoV-2, emergent viruses)<\/li>\n<li>Immunology<\/li>\n<li><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Research topics<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li style=\"list-style-type: none\">\n<ul>\n<li>Structural and functional studies of HIV Env and SARS-CoV-2 Spike<\/li>\n<li>Neutralizing and Fc-effector functions against HIV and SARS-CoV-2<\/li>\n<li>Impact of Env\/Spike conformation on humoral responses<\/li>\n<li>Development of new strategies to eliminate HIV-1-infected cells<\/li>\n<li>Development of new HIV-1 and SARS-CoV-2 inhibitors<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2><strong>Publications<\/strong><\/h2>\n<ul>\n<li style=\"text-align: justify\">Veillette M, D\u00e9sormeaux A, Medjahed H, Gharsallah N, Coutu M, Baalwa J, Guan Y, Lewis G, Ferrari G, Hahn B, Haynes B, Robinson J, Kaufmann D, Bonsignori M, Sodroski J and <strong>Finzi A<\/strong>. Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24352444\"><strong>Journal of Virology<\/strong>. 2014. 88(5):2633-44<\/a>.<\/li>\n<li style=\"text-align: justify\">Richard J., Veillette M., Brassard N., Iyer SS., Roger M., Martin L., Pazgier M.,<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Sch%2526%2523x000f6%253Bn%20A%255Bauth%255D\"> Sch\u00f6n<\/a> A., <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Freire%20E%255Bauth%255D\">Freire<\/a> E., Routy JP., Smith III AB., Park J., Jones DM., Courter JR., Melillo BN., Kaufmann DE., Hahn BH., Permar S., Haynes B, Madani N., Sodroski J., and <strong>Finzi A<\/strong>. CD4 Mimetics Sensitize HIV-1-Infected Cells to ADCC. 2015. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25941367\"><strong>PNAS<\/strong>. 19;112(20):E2687-94<\/a>.<\/li>\n<\/ul>\n<ul style=\"text-align: justify\">\n<li>Pr\u00e9vost J., Anand SP., Rajashekar JK., Zhu L., Richard J., Goyette G., Medjahed H., Gendron-Lepage G., Chen HC., Chen Y., Horwitz JA., Grunst MW., Zolla-Pazner S., Haynes BF., Burton DR., Flavell RA., Kirchhoff F., Hahn BH., Smith III AB., Pazgier M., Nussenzweig MC., Kumar P., and <strong>Finzi A#<\/strong>.\u00a0 HIV-1 Vpu restricts Fc-mediated effector functions in vivo.\u00a0 <strong>Cell Reports<\/strong>. 2022. 41(6):111624. <a href=\"https:\/\/doi.org\/10.1016\/j.celrep.2022.111624\">https:\/\/doi.org\/1016\/j.celrep.2022.111624<\/a><\/li>\n<\/ul>\n<ul style=\"text-align: justify\">\n<li>Laumaea A#., Marchitto L., Ding S., Beaudoin-Bussi\u00e8res G., Pr\u00e9vost J., Gasser R., Chatterjee D., Gendron-Lepage G., Medjahed H., Chen HC., Smith III AB., Ding H., Kappes JC., Hahn BH., Kirchhoff F., Richard J., Duerr R., <strong>Finzi A<\/strong>#.\u00a0 Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity.\u00a0 <strong>Cell Reports<\/strong>. 2022. 42(1):111983. <a href=\"https:\/\/www.cell.com\/cell-reports\/pdf\/S2211-1247(22)01887-3.pdf\">https:\/\/www.cell.com\/cell-reports\/pdf\/S2211-1247(22)01887-3.pdf<\/a><\/li>\n<li>Tauzin A., Gong SY., Beaudoin-Bussi\u00e8res G., V\u00e9zina D., Gasser R., Nault L., Marchitto L., Benlarbi M., Chatterjee D., Nayrac M., Laumaea A., Pr\u00e9vost J., Boutin M., Sannier G., Nicolas A., Bourassa C., Gendron-Lepage G., Medjahed H., Goyette G., Bo Y., Perreault J., Gokool L., Morrisseau C., Arlotto P., Bazin R., Dub\u00e9 M., De Serres G., Brousseau N., Richard J., Rovito R., C\u00f4t\u00e9 M., Tremblay C., Merchetti GC., Duerr R., Martel-Laferri\u00e8re V., Kaufmann DE., and <strong>Finzi A<\/strong>. Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses.\u00a0 <strong>Cell Host and Microbe<\/strong>. 2022. 30:97-109.\u00a0 <a href=\"https:\/\/doi.org\/10.1016\/j.chom.2021.12.004\">https:\/\/doi.org\/10.1016\/j.chom.2021.12.004<\/a><\/li>\n<\/ul>\n<p style=\"text-align: justify\"><span style=\"text-decoration: underline\"> Beaudoin-Bussi\u00e8res G., Chen Y., Ullah I., Pr\u00e9vost J., Tolbert WD., Symmes K., Ding S., Benlarbi M., Gong SY<\/span>., <span style=\"text-decoration: underline\">Tauzin A., Gasser R., Chatterjee D., V\u00e9zina D<\/span>.,<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biography Dr. Finzi graduated from the Universit\u00e9 de Montr\u00e9al. He continues his postgraduate studies in virology in Dr. Joseph Sodroski&#8217;s laboratory at the Dana-Farber Cancer Institute (Harvard Medical School) where [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11407,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7527","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Andr\u00e9s Finzi - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/andres-finzi\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Andr\u00e9s Finzi - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al\" \/>\n<meta property=\"og:description\" content=\"Biography Dr. Finzi graduated from the Universit\u00e9 de Montr\u00e9al. 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