{"id":7534,"date":"2014-07-31T20:55:41","date_gmt":"2014-07-31T20:55:41","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/guy-lemay\/"},"modified":"2021-07-29T18:56:57","modified_gmt":"2021-07-29T17:56:57","slug":"guy-lemay","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/guy-lemay\/","title":{"rendered":"Guy Lemay"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/2018\/02\/Guy-Lemay-2018.png\" alt=\"\" width=\"196\" height=\"196\" class=\"alignnone size-full wp-image-7532\" srcset=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/2018\/02\/Guy-Lemay-2018.png 196w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/2018\/02\/Guy-Lemay-2018-150x150.png 150w\" sizes=\"auto, (max-width: 196px) 100vw, 196px\" \/><\/p>\n<p><\/div>\n<table style=\"width: 288px\">\n<tbody>\n<tr>\n<td style=\"width: 81px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 357px\">Professor<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 81px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 357px\">D\u00e9partement de microbiologie, infectiologie et immunologie<br \/>\nPavillon Roger-Gaudry<br \/>\nUniversit\u00e9 de Montr\u00e9al<br \/>\nC.P. 6128, Succ. Centre-ville<br \/>\nMontr\u00e9al (Qu\u00e9bec)\u00a0 H3C 3J7<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 81px\"><strong>Room:<\/strong><\/td>\n<td style=\"width: 357px\">Office: S-627<br \/>\nLab:U-607<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 81px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 357px\">Office: 514 343-2422<br \/>\nLab: 514 343-6111, ext. 3146<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 81px\"><strong>Fax:<\/strong><\/td>\n<td style=\"width: 357px\">514 343-5701<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 81px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 357px\"><a href=\"mailto:guy.lemay@umontreal.ca\">guy.lemay@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><br \/>\n<hr\/><\/p>\n<h2><strong>Biography<\/strong><\/h2>\n<p style=\"text-align: justify\">Dr. Guy Lemay holds a bachelor\u2019s degree and a master\u2019s degree in microbiology and immunology from the Universit\u00e9 de Montr\u00e9al. His master\u2019s work under the direction of Dr. Paul Jolicoeur at the Montreal Clinical Research Institute focused on the integration of retroviral DNA in tumoral DNA. Subsequently, he pursued his doctoral studies under the direction of Dr. Stewart Millward, Department of Biochemistry, McGill University. His work allowed to demonstrate the importance of a reovirus protein in the control of protein synthesis during infection. Dr. Lemay finally developed his expertise in enzymology and protein biochemistry during a postdoctoral fellowship under the direction of Dr. Guy Boileau, Department of Biochemistry, Universit\u00e9 de Montr\u00e9al. He was subsequently recruited in the Department of Microbiology and Immunology in 1989 and promoted to full professor in 2000. As the recipient of a scholarship from the Fonds de recherche en sant\u00e9 du Qu\u00e9bec from 1991 to 2003, he developed several research aspects mainly on replication of mammalian retroviruses and reoviruses. Recently, most of his research is focused on the replication of the latter to better understand their ability to destroy cancer cells. In recent years he has also been actively involved in lectures for the general public, especially on the history of virology and infectious diseases. He has also been the recipient of an award from the Association francophone pour le savoir in 2010 and the excellence of his teaching activities has been recognized by a prize from the Universite\u0301 de Montre\u0301al in 2015. Over the years, Dr. Lemay has also been actively involved in the institution as the head of the graduate and undergraduate programs of the department as well as departmental chairman, among others.<\/p>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2><strong>Team<\/strong><\/h2>\n<ul>\n<li>Guillaume David Despr\u00e9s, M.Sc. student<\/li>\n<li>Simon Boudreault, PhD student (co-supervision, Universit\u00e9 de Sherbrooke)<\/li>\n<\/ul>\n<hr\/>\n<h2><strong>Theme<\/strong><\/h2>\n<ul>\n<li>Virology<\/li>\n<\/ul>\n<hr\/>\n<h2><strong>Research topics<\/strong><\/h2>\n<ul>\n<li>Viral and cellular determinants of interferon response during mammalian reovirus infection<\/li>\n<li>Adaptation mechanisms of mammalian reovirus during viral persistence in cell culture<\/li>\n<li>Reovirus reverse genetics<\/li>\n<li>Enzyme activities of mammalian reovirus capsid proteins<\/li>\n<li>Studies of transcriptome and cellular alternative splicing modifications during viral infection (in collaboration with Dr Martin Bisaillon, Universit\u00e9 de Sherbrooke)<\/li>\n<\/ul>\n<hr\/>\n<h2><strong>Publications <\/strong><\/h2>\n<ul>\n<li>Lanoie, D., C\u00f4t\u00e9, S., Degeorges, E. and Lemay, G. (2019) A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30578938\/\"><strong>Virology<\/strong> 528:73-79. doi:10.1016\/j.virol.2018.12.010<\/a><\/li>\n<li>Lanoie, D., Boudreault, S., Bisaillon, M. and Lemay, G. (2019) How many mammalian reovirus proteins are involved in the control of the interferon response? <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31234302\/\"><strong>Pathogens<\/strong> 8:83. doi:10.3390\/pathogens8020083<\/a><\/li>\n<li>Lanoie, D. and Lemay, G. (2018) Multiple proteins differing between laboratory stocks of mammalian orthoreoviruses affect both virus sensitivity to interferon and induction of interferon production during infection. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29382551\/\"><strong>Virus Research<\/strong> 247:40-46. doi:10.1016\/j.virusres.2018.01.009<\/a><\/li>\n<li>Boudreault, S., Martenon-Brodeur, C., Caron, M., Garant, J.-M., Tremblay, M.-P., Armero, V.E.S., Durand, M., Lapointe, E., Thibault, P., Tremblay-L\u00e9tourneau, M., Perreault, J.-P., Scott, M.S., Lemay, G. and Bisaillon, M. (2016) Global profiling of the cellular alternative RNA splicing landscape during virus-host interactions. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27598998\"><strong>PloS ONE<\/strong> 11:e-0161914-21<\/a>.<\/li>\n<\/ul>\n<p style=\"text-align: justify\">\n","protected":false},"excerpt":{"rendered":"<p>Biography Dr. Guy Lemay holds a bachelor\u2019s degree and a master\u2019s degree in microbiology and immunology from the Universit\u00e9 de Montr\u00e9al. His master\u2019s work under the direction of Dr. Paul [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11407,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7534","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Guy Lemay - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/guy-lemay\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Guy Lemay - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al\" \/>\n<meta property=\"og:description\" content=\"Biography Dr. Guy Lemay holds a bachelor\u2019s degree and a master\u2019s degree in microbiology and immunology from the Universit\u00e9 de Montr\u00e9al. 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