{"id":7540,"date":"2014-07-30T19:04:54","date_gmt":"2014-07-30T19:04:54","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/marc-drolet\/"},"modified":"2018-07-16T16:18:59","modified_gmt":"2018-07-16T15:18:59","slug":"marc-drolet","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/marc-drolet\/","title":{"rendered":"Marc Drolet"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2215\" alt=\"silhouette-fille-100\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/silhouette-100.jpg\" width=\"100\" height=\"150\" \/><\/p>\n<p><\/div>\n<table style=\"width: 343px\">\n<tbody>\n<tr>\n<td style=\"width: 76px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 263px\">Full time professor<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 76px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 263px\">D\u00e9partement de microbiologie, infectiologie et immunologie<br \/>\nUniversit\u00e9 de Montr\u00e9al<br \/>\nC.P. 6128, Succ. Centre-ville<br \/>\nMontr\u00e9al (Qu\u00e9bec)<br \/>\nH3C 3J7<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 76px\"><strong>Room:<\/strong><\/td>\n<td style=\"width: 263px\">Office: R-612, Pavillon Roger-Gaudry<br \/>\nLabo: R-611, Pavillon Roger-Gaudry<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 76px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 263px\">Office: 514-343-5796<br \/>\nLabo: 514-343-6111, ext. 1899<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 76px\"><strong>Fax:<\/strong><\/td>\n<td style=\"width: 263px\">514-343-5701<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 76px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 263px\"><a href=\"mailto:marc.drolet@umontreal.ca\">marc.drolet@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><br \/>\n<hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>B<\/strong><strong>iography<\/strong><\/h2>\n<p style=\"text-align: justify\">Dr. Drolet completed his PhD studies in bacterial genetics, under the direction of Dr. Alexandre Sasarman, Department of Microbiology and Immunology, Universit\u00e9 de Montr\u00e9al. He then completed two postdoctoral fellowships in Montreal, one at the Biotechnology Research Institute under Dr. Peter Lau and the other at the Ludwig Institute for Cancer Research with Dr. Alain Nepveu. His third postdoctoral fellowship with Dr. Leroy Liu at Johns Hopkins Medical School in Baltimore focused on the study of topoisomerases and the topology of DNA. In September 1993, he began his career as an assistant professor in the Department of Microbiology and Immunology at the Universit\u00e9 de Montr\u00e9al. Since 2005 he is a full professor in the department and he was acting director of this department from May 2011 to September 2012. The results of Dr Drolet&#8217;s work on topoisomerases and DNA topology in the <em>E. coli<\/em> model organism are highly cited in the field and have had a major impact on understanding the mechanisms of genome maintenance and expression in prokaryotes and eukaryotes. Dr. Drolet was a scholar of the FRSQ. He serves as an external referee for many scientific journals and sits on several national pairs committees. He has chaired the committee for the creation of the undergraduate program in microbiology and immunology and has served on many institutional committees.<br \/>\n<hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Team<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Nadia Labbaci (\u00e9tudiante \u00e0 la ma\u00eetrise)<\/li>\n<li>Julien Brochu (\u00e9tudiant \u00e0 la ma\u00eetrise)<\/li>\n<li>\u00c9milie Vlachos (programme Honor)<\/li>\n<li>Sarah Sutherland (stagiaire 1<sup>er<\/sup> cycle)<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Theme<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Bacteriology<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Research topics<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Roles of DNA topoisomerases in the maintenance of genome stability in bacteria.<\/li>\n<li>Mechanisms of adaptive mutagenesis.<\/li>\n<li>Mechanisms of R-loop formation.<\/li>\n<li>Characterization of DNA topoisomerases from <em>Campylobacter jejuni<\/em>.<\/li>\n<li>The use of DNA topoisomerases as cellular targets in antimicrobial chemotherapy.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Publications<\/strong><\/h2>\n<ul>\n<li style=\"text-align: justify\">V. Usongo, M. Martel, A. Balleydier et M. Drolet (2016). Mutations reducing replication from R-loops suppress the defects of growth, chromosome segregation and DNA supercoiling in cells lacking topoisomerase I and RNase HI activity. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26947024\"><em>DNA Repair<\/em>. 40:1-17<\/a>.<\/li>\n<li style=\"text-align: justify\">M. Martel*, A. Balleydier*, A. Sauriol* et M. Drolet (2015). Constitutive stable DNA replication in <em>Escherichia coli<\/em> cells lacking type 1A topoisomerase activity. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26444226\"><em>DNA Repair<\/em>. 35:37-47<\/a>.<\/li>\n<li style=\"text-align: justify\">Usongo V et Drolet M. 2014. Roles of type 1A topoisomerases in genome maintenance in <em>Escherichia coli<\/em>. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25102178\">PLoS Genet.\u00a0Aug 7;10(8):e1004543<\/a>.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Biography Dr. Drolet completed his PhD studies in bacterial genetics, under the direction of Dr. Alexandre Sasarman, Department of Microbiology and Immunology, Universit\u00e9 de Montr\u00e9al. He then completed two postdoctoral [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11407,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7540","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Marc Drolet - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/marc-drolet\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Marc Drolet - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al\" \/>\n<meta property=\"og:description\" content=\"Biography Dr. Drolet completed his PhD studies in bacterial genetics, under the direction of Dr. Alexandre Sasarman, Department of Microbiology and Immunology, Universit\u00e9 de Montr\u00e9al. 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