{"id":7565,"date":"2015-01-13T16:44:29","date_gmt":"2015-01-13T15:44:29","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/nicolas-chomont\/"},"modified":"2021-02-16T20:37:51","modified_gmt":"2021-02-16T19:37:51","slug":"nicolas-chomont","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/nicolas-chomont\/","title":{"rendered":"Nicolas Chomont"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Chomont-Nicolas-f-222x300.jpg\" alt=\"Chomont Nicolas f\" width=\"222\" height=\"300\" class=\"alignnone size-medium wp-image-4613\" \/><\/p>\n\n<p><\/div>\n<p><a href=\"http:\/\/www.cancurehiv.org\"><\/a><\/p>\n<table style=\"width: 273px\">\n<tbody>\n<tr>\n<td style=\"width: 73px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 262px\">Associate research professor<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 262px\">Centre de Recherche du CHUM<br \/>\nAxe Immunopathologie<br \/>\n900 rue Saint-Denis<br \/>\nTour Viger, Pavillon R<br \/>\nMontreal, QC H2X 0A9<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73px\"><strong>Room:<\/strong><\/td>\n<td style=\"width: 262px\">Office: R09.430<br \/>\nLabo: R09.300<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 262px\">Office: 514-890-8000, ext. 31266<br \/>\nLabo: 514-890-8000, ext. 31247<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73px\"><strong>Fax:<\/strong><\/td>\n<td style=\"width: 262px\">514-412-7936<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 262px\"><a href=\"mailto:nicolas.chomont@umontreal.ca\">nicolas.chomont@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><a href=\"http:\/\/www.cancurehiv.org\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-300x111.jpg\" alt=\"CanCURE logo_FR_COLOR\" width=\"205\" height=\"76\" class=\"wp-image-4135 alignleft\" srcset=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-300x111.jpg 300w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-1024x378.jpg 1024w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-200x74.jpg 200w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-295x109.jpg 295w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-198x73.jpg 198w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR-604x223.jpg 604w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/CanCURE-logo_FR_COLOR.jpg 1731w\" sizes=\"auto, (max-width: 205px) 100vw, 205px\" \/><\/a><\/div><br \/>\n<hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Biography<\/strong><\/h2>\n<p style=\"text-align: justify\">Dr. Nicolas Chomont is an Associate research professor in the Department of Microbiology, Infectiology and Immunology at the Universit\u00e9 de Montr\u00e9al. His laboratory is located at the Research Center of the CHUM (CRCHUM). Dr. Chomont received his doctorate in medical virology at the Pierre and Marie Curie University (Paris VI) under the direction of Prof. Laurent B\u00e9lec in the laboratory of Prof. Michel Kazatchkine. He studied the interactions between HIV and genital mucosa and their implications for the sexual transmission of the virus. Between 2004 and 2009, he completed a postdoctoral internship in Dr. Rafick S\u00e9kaly&#8217;s laboratory at the Universit\u00e9 de Montr\u00e9al and the CRCHUM. His work has led to the identification of the cellular reservoirs of HIV that are responsible for the persistence of the virus during antiretroviral therapies. Dr. Chomont then moved to VGTI-Florida where he was named &#8220;Associate Member&#8221;. As an independent researcher, he has continued to characterize viral reservoirs as the major obstacle to the eradication of HIV. Since January 2015, Dr. Chomont has joined the Universit\u00e9 de Montr\u00e9al and the CRCHUM where he leads a research program aimed at dissecting the molecular and immunological mechanisms involved in viral latency and developing new therapeutic strategies aimed at Elimination of HIV reservoirs.<br \/>\n<hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Team<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>R\u00e9mi Fromentin, PharmD, PhD, Associ\u00e9 de recherche<\/li>\n<li>Am\u00e9lie Pagliuzza, M.Sc., Assistante de recherche<\/li>\n<li>Cesar Trifone, PhD,\u00a0Stagiaire postdoctoral<\/li>\n<li>Caroline Dufour, \u00e9tudiante au doctorat<\/li>\n<li>Armando Espinosa-Ortiz, \u00e9tudiant au doctorat<\/li>\n<li>Alessandro Modica, \u00e9tudiant \u00e0 la ma\u00eetrise<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Themes<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Immunology<\/li>\n<li>Virology<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Research topics<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Characterization of cellular and anatomical reservoirs of HIV during triple therapy<\/li>\n<li>Study of the molecular mechanisms of HIV latency<\/li>\n<li>Development of new tools to characterize and quantify HIV reservoirs<\/li>\n<li>Development of therapeutic strategies to eliminate reservoirs of HIV<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Publications<\/strong><\/h2>\n<ul>\n<li style=\"text-align: justify\">Gantner P, Pagliuzza A, Pardons M, Ramgopal M, Routy JP, Fromentin R, <strong>Chomont N.<\/strong> 2020. Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32796830\/\">Nature communications. 11(1):4089<\/a>.<\/li>\n<li style=\"text-align: justify\">Dufour C, Gantner P, Fromentin R, <strong>Chomont N.<\/strong> 2020. The multifaceted nature of HIV latency. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32609095\/\">J Clin Invest. 130(7):3381-3390<\/a>.<\/li>\n<li style=\"text-align: justify\">Massanella M, Puthanakit T, Leyre L, Jupimai T, Sawangsinth P, de Souza M, Suntarattiwong P, Kosalarksa P, Borkird T, Kanjanavanit S, Chokephaibulkit K, Hansudewechakul R, Petdachai W, Mitchell JL, Robb ML, Trautmann L, Ananworanich J, <strong>Chomont N.<\/strong> 2020. Continuous prophylactic ARV\/ART since birth reduces seeding and persistence of the viral reservoir in vertically HIV-infected children. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32504081\/\">Clin Infect Dis<\/a>.<\/li>\n<li style=\"text-align: justify\">Leyre L, Kroon E, Vandergeeten C, Sacdalan C, Colby DJ, Buranapraditkun S, Schuetz A, Chomchey N, de Souza M, Bakeman W, Fromentin R, Pinyakorn S, Akapirat S, Trichavaroj R, Chottanapund S, Manasnayakorn S, Rerknimitr R, Wattanaboonyoungcharoen P, Kim JH, Tovanabutra S, Schacker TW, O&#8217;Connell R, Valcour VG, Phanuphak P, Robb ML, Michael N, Trautmann L, Phanuphak N, Ananworanich J, <strong>Chomont N<\/strong>, RV254\/Search010. 2020. Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection. S<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32132218\/\">ci Transl Med. 12(533)<\/a>.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biography Dr. Nicolas Chomont is an Associate research professor in the Department of Microbiology, Infectiology and Immunology at the Universit\u00e9 de Montr\u00e9al. His laboratory is located at the Research Center [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":0,"parent":11407,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7565","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nicolas Chomont - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/nicolas-chomont\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nicolas Chomont - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al\" \/>\n<meta property=\"og:description\" content=\"Biography Dr. Nicolas Chomont is an Associate research professor in the Department of Microbiology, Infectiology and Immunology at the Universit\u00e9 de Montr\u00e9al. 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