{"id":7743,"date":"2014-07-28T14:50:35","date_gmt":"2014-07-28T14:50:35","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/ali-ahmad\/"},"modified":"2020-09-23T21:37:47","modified_gmt":"2020-09-23T20:37:47","slug":"ali-ahmad","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/ali-ahmad\/","title":{"rendered":"Ali Ahmad"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2154\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/silhouette-100.jpg\" alt=\"silhouette-100\" width=\"100\" height=\"150\" \/><\/p>\n<p><\/div>\n<table style=\"width: 364px\">\n<tbody>\n<tr>\n<td style=\"width: 63px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 287px\">Honorary professor<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 287px\">Centre de recherche du CHU Ste-Justine<br \/>\n3175, ch. C\u00f4te-Ste-Catherine<br \/>\nMontr\u00e9al (Qu\u00e9bec)\u00a0 H3T 1C5<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 287px\">514 345 4931, ext.\u00a06157<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 287px\"><a href=\"mailto:ali.ahmad@recherche-ste-justine.qc.ca\">ali.ahmad@recherche-ste-justine.qc.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<hr\/>\n<h2><strong>Biography<\/strong><\/h2>\n<table style=\"width: 541px\">\n<tbody>\n<tr>\n<td style=\"width: 195px\">1971-1975<\/td>\n<td style=\"width: 201px\">DVM<\/td>\n<td style=\"width: 249px\">University of Agriculture Faisalabad (Pakistan)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1976-1983<\/td>\n<td style=\"width: 201px\">MSc<\/td>\n<td style=\"width: 249px\">University of Agriculture Faisalabad (Pakistan)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1976-1985<\/td>\n<td style=\"width: 201px\">Lecturer<\/td>\n<td style=\"width: 249px\">Anatomy Department, University of Agriculture Faisalabad<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1985-1989<\/td>\n<td style=\"width: 201px\">PhD<\/td>\n<td style=\"width: 249px\">Cornell University (USA)<\/p>\n<p>RG Bell (Professor)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1990-1995<\/td>\n<td style=\"width: 201px\">Postdoc<\/td>\n<td style=\"width: 249px\">University of Montreal<\/p>\n<p>J Menezes (Professor)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1996-1997<\/td>\n<td style=\"width: 201px\">Res. Associate<\/td>\n<td style=\"width: 249px\">University of Montreal<\/p>\n<p>J Menezes (Professor)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1997-<\/td>\n<td style=\"width: 201px\">Researcher<\/td>\n<td style=\"width: 249px\">Research Center CHU Ste-Justine\/ Univerity of Montreal<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">1997-2006<\/td>\n<td style=\"width: 201px\">Assistant Prof-Research<\/td>\n<td style=\"width: 249px\">Department of Microbiology, Infectiology &amp; Immunology\/University of Montreal.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 195px\">2006-<\/td>\n<td style=\"width: 201px\">Associate Prof -Research<\/td>\n<td style=\"width: 249px\">Department of Microbiology, Infectiology &amp; Immunology\/University of Montreal.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr\/>\n<h2><strong>Team<\/strong><\/h2>\n<ul>\n<li>Ayoub Abulkhir, M.Sc.<\/li>\n<li>Suzanne Samarani, Ph.D.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr\/>\n<h2><strong>Themes<\/strong><\/h2>\n<ul>\n<li>Immunology<\/li>\n<li>Virology<\/li>\n<li>Inflammation<\/li>\n<\/ul>\n<hr\/>\n<h2><strong>Research topics <\/strong><\/h2>\n<ul>\n<li>Immunology of HIV infection\/AIDS.<\/li>\n<li>Immunopathogenesis of Crohn disease<\/li>\n<li>Innate immunity in cancer (leukemia)<\/li>\n<\/ul>\n<hr\/>\n<h2 style=\"text-align: justify\"><strong>Publications (selected)<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Kumar V, Ahmad A. Role of MAIT cells in the immunopathogenesis of inflammatory diseases: New players in old game. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Kumar+V%2C+Ahmad+A.+mait\"><strong>Int Rev Immunol<\/strong>. 2018 Mar 4;37(2):90-110<\/a>.<\/li>\n<li>Allam O, Samarani S, Jenabian MA, Routy JP, Tremblay C, Amre D, Ahmad A. Differential synthesis and release of IL-18 and IL-18 Binding Protein from human platelets and their implications for HIV infection. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27914933\"><strong>Cytokine<\/strong>. 2017 Feb; 90: 144-154<\/a>.<\/li>\n<li>Abulkhir A, Samarani S, Amre D, Duval M, Haddad E, Sinnett D, Leclerc JM, Diorio C, Ahmad A. A protective role of IL-37 in cancer: a new hope for cancer patients.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Abulkhir+A%2C+Samarani+S%2C+Amre+D%2C+Duval+M%2C+Haddad+E\"><strong> J Leukoc Biol<\/strong>. 2017 Feb; 101(2):395-406<\/a>.<\/li>\n<li>Ahmad A, Rinaldo CR. A novel anti-HIV immunotherapy to cure HIV. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Ahmad+A%2C+Rinaldo+C\"><strong>AIDS<\/strong>. 2017 Jan 28; 31(3):447-449<\/a>.<\/li>\n<li>Iannello A, Samarani S, Allam O, Jenabian MA, Mehraj V, Amre D, Routy JP, Tremblay C, Ahmad A. A potentially protective role of IL-18 Binding Protein in HIV-infected Long-Term Non-Progressors. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Iannello+A%2C+Samarani+S%2C+Allam+O%2C+Jenabian\"><strong>Cytokine<\/strong>. 2017 Feb; 90:96-99<\/a>.<\/li>\n<li>Ahmad A, Mehraj V, Jenabian MA, Samarani S, Tremblay C, Routy JP. Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections: challenges and new opportunities. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27351927\"><strong>AIDS<\/strong>. 2016 Jul 17; 30 (11):1839-41<\/a>.<\/li>\n<li>Suzanne Samarani, Ossama Allam, Patrick Sagala, Zainab Aldabah, Mohammad-Ali Jenabian, Vikram Mehraj, C\u00e9cile Tremblay, Jean-Pierre Routy, Devendra Amre and Ali Ahmad. Imbalanced production of IL-18 and its antagonist in human diseases, and its implications for HIV-1 infection. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26898120\"><strong>Cytokine<\/strong>; 2016 Jun; 82:38-51<\/a>.<\/li>\n<li>Allam O, Samarani S, Ahmad A. Mesenchymal Stem Cell Therapy in HIV-infected HAART-treated Non-immune Responders restores Immune Competence. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23925382\"><strong>AIDS<\/strong>. 2013; May 15; 27(8):1349-52<\/a>.<\/li>\n<li>Allam O, Samarani S, Ahmad A. Microbial translocation and AIDS-associated lymphomas: crux of the problem. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23291542\"><strong>AIDS<\/strong>. 2013 Jan 28; 27(3):477-8<\/a>.<\/li>\n<li>Allam O, Samarani S, Ahmad A. 2011. Hammering out HIV-1 incidence with Hamming Distance. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21997490\"><strong>AIDS<\/strong>, 25 (16): 2047-8<\/a>.<\/li>\n<li>Zaema Almalte, Suzanne Samarani, Alexandre Iannello, Olfa Debbeche, Devendra K Amre, Daniel Sinnett and Ali Ahmad. 2011. Association of activating Killer-cell Immunoglobulin-like Receptor genes with decreased risk for developing B cell acute lymphoblastic leukemia in children. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21613255\"><strong>Blood<\/strong> 118(5):1323-8<\/a>.<\/li>\n<li>Alexandre Iannello, Mohamed-Rachid Boulassel, Suzanne Samarani, C\u00e9cile Tremblay, Emil Toma, Jean-Pierre Routy and Ali Ahmad. 2010. IL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replication. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20103765\"><strong>J Leuk Biology<\/strong> 87(5): 857-67<\/a>.<\/li>\n<li>Alexandre Iannello, Suzanne Samarani, Mohamed-Rachid Boulassel, C\u00e9cile Tremblay, Emil Toma, Jean-Pierre Routy and Ali Ahmad. 2010. HIV causes imbalance in production of interleukin-18 and its natural antagonist in HIV-infected AIDS patients: implications for enhanced viral replication. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20078197\"><strong>Journal of Infectious Diseases<\/strong> 201 (4): 608-17<\/a>.<\/li>\n<li>Alexandre Iannello, Suzanne Samarani, Olfa Debbeche, Mohamed-Rachid Boulassel, C\u00e9cile Tremblay, Emil Toma, Jean-Pierre Routy and Ali Ahmad. 2010. Dynamics and consequences of IL-21 production in HIV-infected persons: A longitudinal and cross sectional study. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19949086\"><strong>Journal of Immunology<\/strong> 184 (1): 114-26<\/a>.<\/li>\n<li>Alexandre Iannello, Suzanne Samrani, Olfa Debbeche, Rasheed Ahmad, Mohamed-Rashid Boulassel, C\u00e9cile Tremblay, Emil toma, Jean-Pierre Routy and Ali Ahmad.2009. Potential role of IL-18 in the immunopathogenesis of AIDS: involvement in fratricidal killing of NK cells and enhanced HIV replication. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19339355\"><strong>Journal of Virology<\/strong> 83(12): 5999-6010<\/a>.<\/li>\n<li>Alexandre Iannello, Suzanne Samarani, Olfa Debbeche, Mohamed-Rachid Boulassel, C\u00e9cile Tremblay, Emil Toma, Jean-Pierre Routy and Ali Ahmad. 2009. Role of Interleukin-18 in the development and pathogenesis of AIDS. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19654853\"><strong>AIDS Reviews<\/strong>, 11(3): 115-25<\/a>.<\/li>\n<li>Iannello A, Debbeche O, Samarani S, and Ahmad A. 2008. Antiviral NK Cell Responses in HIV Infection: I. NK cell receptor genes as determinants of resistance to HIV infection and progression to AIDS. First part of An Editor-solicited state-of-the-art review article on the subject. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18388298\"><strong>Journal of Leukocyte Biology<\/strong> 84(1): 1-26<\/a>.<\/li>\n<li>Ahmad R, Iannello A, Samarani S, Toma E, Morisset R, Grosley M, Ahmad A. 2006. Contribution of platelet activation to plasma IL-18 concentrations in HIV-infected AIDS patients. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16954739\"><strong>AIDS<\/strong> 20 (14): 1907-9<\/a>.<\/li>\n<li>Ahmad A and F. Alvarez. 2004. Role of NK and NKT Cells in the immunopathogenesis of HCV-induced Hepatitis. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Ahmad+A++Alvarez+2004\"><strong>Journal of Leukocyte Biology<\/strong>. 76: 743-759<\/a>.<\/li>\n<li>Ahmad, R., S.T.A.K. Sindhu, E. Toma, R. Morisset, and A. Ahmad. 2002. Elevated levels of circulating IL-18 in HIV-infected individuals: Role of peripheral blood mononuclear cells and implications for AIDS pathogenesis. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12438570\"><strong>J. Virology<\/strong> 76(24): 12448-56<\/a>.<\/li>\n<li>A. Subbramanian, J.W. Xu, E. Toma, R. Morisset, E. Cohen, J. Menezes, A. Ahmad. 2002. Comparison of human immunodeficiency virus (HIV)-specific infection-enhancing and \u2013inhibiting antibodies in AIDS patients. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12037078\"><strong>J. Clin. Microbiology<\/strong> 40:2141-2146<\/a>.<\/li>\n<li>Ahmad R, S.T.A.K. Sindhu, P. Tran, E. Toma, R. Morisset, J. Menezes, A. Ahmad. 2001. Modulation of the expression of the MHC class I-binding natural killer (NK cell receptors and NK activity in relation to viral load in HIV-infected\/AIDS patients.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11596074\"><strong> J. Medical Virology<\/strong> 65:431-440<\/a>.<\/li>\n<li>Ahmad R, S.T.A.K. Sindhu, E. Toma, R. Morisset, J. Vincilitte, J. Menezes, A. Ahmad. 2001. Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11403230\"><strong>J. Clinical Immunology<\/strong> 21:227-233<\/a><\/li>\n<li>Ahmad A, E. Sharif-Askari, L. Fawaz, J. Menezes. 2000. Innate immune response of human host to infection with Herpes simplex virus type-1: In vitro control of infection by enhanced natural killer cytolytic activity via IL-15 induction. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10906173\"><strong>J. Virology<\/strong> 74:7196-7203<\/a>.<\/li>\n<li>Xu JW, J. Menezes, U. Prasad, A. Ahmad. 1999. Elevated serum levels of transforming growth factor-\uf0621 in Epstein-Barr virus-associated nasopharyngeal carcinoma patients. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10404092\"><strong>Int. J. Cancer<\/strong> 84: 396-399<\/a>.<\/li>\n<li>Ahmad A, J. Menezes. 1997. The binding of Epstein-Barr virus to human platelets causes the release of transforming growth factor-\u00df. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9378987\"><strong>J. Immunology<\/strong>. 159: 3984-3988<\/a>.<\/li>\n<li>Ahmad A, J. Menezes. 1996. Antibody-dependent cellular cytotoxicity in HIV-infections <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8641559\"><strong>FASEB Journal<\/strong> 10: 258-266<\/a>.<\/li>\n<li>Ahmad A, J. Menezes. 1996. Defective killing activity against gp120\/41-expressing human erythroleukaemic K562 cell line by monocytes and natural killer cells from HIV-infected individuals. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8838701\"><strong>AIDS<\/strong> 10: 143-149<\/a>.<\/li>\n<li>Ahmad A, J. Menezes. 1995. Positive correlation between natural killer and gp120 specific antibody dependent cellular cytotoxic effector functions of the peripheral blood mononuclear cells in HIV-infected individuals. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7552474\"><strong>J. Acq. Immune Deficiency Syndrome &amp; Human Retrovirology<\/strong> 10: 115-119<\/a>.<\/li>\n<li>Ahmad A, A. Ladha, E.A. Cohen, J. Menezes. 1993. Stable expression of the transfected HIV-1 env gene in a human B cell line: Characterization of gp120-expressing clones and immunobiological studies. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8421893\"><strong>Virology<\/strong> 192: 447-457<\/a>.<\/li>\n<li>Ahmad A, C.H. Wang, R.G. Bell. 1991. A role for IgE in intestinal immunity: Expression of rapid expulsion of Trichinella spiralis in rats transfused with IgE and thoracic duct lymphocytes.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2026881\"><strong> Journal of Immunology<\/strong> 146: 3563-3570<\/a>.<\/li>\n<li>Korenaga M, C.H. Wang, R.G. Bell, D. Zhu, A. Ahmad. 1989. Intestinal immunity to Trichinella spiralis is a property of OX8- OX22- T helper cells that are generated in the intestine.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=ahmad+bell+Wang+1989\"> <strong>Immunology<\/strong>. 66: 588-594<\/a>.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Biography 1971-1975 DVM University of Agriculture Faisalabad (Pakistan) 1976-1983 MSc University of Agriculture Faisalabad (Pakistan) 1976-1985 Lecturer Anatomy Department, University of Agriculture Faisalabad 1985-1989 PhD Cornell University (USA) RG Bell [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7743","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ali Ahmad - D\u00e9partement de microbiologie, infectiologie et immunologie - 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