{"id":7864,"date":"2014-08-04T19:23:09","date_gmt":"2014-08-04T19:23:09","guid":{"rendered":"https:\/\/microbiologie.umontreal.ca\/mariela-segura\/"},"modified":"2018-07-17T16:27:05","modified_gmt":"2018-07-17T15:27:05","slug":"mariela-segura","status":"publish","type":"page","link":"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/mariela-segura\/","title":{"rendered":"Mariela Segura"},"content":{"rendered":"<div  class=\" fiche-chercheur  \">\n<div class=\"img noLightbox\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"99\" height=\"90\" class=\"alignnone wp-image-3619\" alt=\"Segura Mariela\" src=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-300x273.jpg\" srcset=\"https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-300x273.jpg 300w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-1024x933.jpg 1024w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-200x182.jpg 200w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-295x268.jpg 295w, https:\/\/microbiologie.umontreal.ca\/wp-content\/uploads\/sites\/12\/Segura-Mariela-604x550.jpg 604w\" sizes=\"auto, (max-width: 99px) 100vw, 99px\" \/><\/p>\n<p><\/div>\n\n<table style=\"width: 430px\">\n<tbody>\n<tr>\n<td style=\"width: 77px\"><strong>Title:<\/strong><\/td>\n<td style=\"width: 339px\">Full time professor (accredited)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 77px\"><strong>Address:<\/strong><\/td>\n<td style=\"width: 339px\">D\u00e9partement de pathologie et microbiologie<br \/>\nFacult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire<br \/>\nUniversit\u00e9 de Montr\u00e9al &#8211; Campus de St-Hyacinthe<br \/>\n3200, rue Sicotte<br \/>\nSt-Hyacinthe (Qu\u00e9bec) J2S 2M2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 77px\"><strong>Room:<\/strong><\/td>\n<td style=\"width: 339px\">3923<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 77px\"><strong>Phone:<\/strong><\/td>\n<td style=\"width: 339px\">514-343-6111, ext. 0080<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 77px\"><strong>Email:<\/strong><\/td>\n<td style=\"width: 339px\"><a href=\"mailto:mariela.segura@umontreal.ca\">mariela.segura@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<hr\/>\n<h2 style=\"text-align: justify\"><strong>Biography<\/strong><\/h2>\n<p style=\"text-align: justify\">Mariela Segura is an immunologist and Professor at the University of Montreal. She received her M.Sc. and Ph.D. from the Faculty of Medicine of the University of Montreal, where she became interested in host-pathogen interactions. During two post-doctoral trainings (Infectious Disease Unit at Laval University; and McGill Centre for the Study of Host Resistance) she acquired expertise on cellular biology and signalling pathways as well as immunomodulation by parasites. Dr. Segura started her independent research career at the Faculty of Veterinary Medicine in 2007 after being granted a FRQS career award. She is known for research in the areas of infectious diseases and the underlying innate and adaptive immune responses, with a particular focus on the interactions of encapsulated streptococci (such as <em>Streptococcus suis<\/em> and Group B <em>Streptococcus<\/em>) with the components of the immune system.<\/p>\n<p style=\"text-align: justify\">Segura\u2019s laboratory applies multidisciplinary approaches, from biochemistry to cellular and molecular immunology, to dissect the role of bacterial capsular polysaccharides (CPSs) on the immunopathogenesis of the disease caused by pathogenic streptococci. Segura\u2019s team focuses on CPS modulation of antigen-presenting cells, more particularly dendritic cells, and down-stream effect on the development of adaptive immunity, including analyses of T and B cell functions.\u00a0 An interconnected research axe seeks out vaccine development against <em>Streptococcus suis<\/em>, an emerging swine and human pathogen.<\/p>\n<p style=\"text-align: justify\">Segura\u2019s research contributions have been recognized with 19 prizes and awards, a few of which are the UNESCO-L\u2019Or\u00e9al Canada for Women in Science Research Excellence Award; the \u2018Zoetis (Pfizer)\u2019 Award of Excellence in Research; the \u2018Fisher Award\u2019 of the Canadian Society of Microbiologists in recognition of outstanding contributions to Microbiology as a profession; and the Women of Distinction Award in Science and Technology. Dr Segura is author or co-author of 115 total publications, including research articles, review articles and book chapters. She has contributed to the training of 75 graduate and undergraduate students in her laboratory.<\/p>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Team\u00a0<\/strong><\/h2>\n<p style=\"text-align: justify\">To come up<\/p>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Theme<\/strong><\/h2>\n<p style=\"text-align: justify\">Immunology<\/p>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Research topics<\/strong><\/h2>\n<ul style=\"text-align: justify\">\n<li>Characterization of the interactions between encapsulated bacteria and immune cells. Role of the capsular polysaccharide (CPS) in the modulation of the innate and adaptive immune responses. Glycoconjugate vaccine development.<\/li>\n<li>Studied bacteria: Group B <em>Streptococcus<\/em> (GBS) and <em>Streptococcus suis<\/em><\/li>\n<li>Animal model: mice and swine<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><hr\/><\/p>\n<h2 style=\"text-align: justify\"><strong>Publications<\/strong><\/h2>\n<p style=\"text-align: justify\"><strong>(2018, 2017, 2016, and few selected from 2015-2014)<\/strong><\/p>\n<ol>\n<li style=\"text-align: justify\">Roy, D., D. Takamatsu, M. Okura, G. Goyette-Desjardins, M.R. Van Calsteren, A. Dumesnil, M. Gottschalk, and <strong>M Segura<\/strong>. <em>Streptococcus suis<\/em> sialyltransferase exhibits alpha2-6 activity in Group B <em>Streptococcus<\/em>. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29666608\"><strong>Frontiers in Microbiology<\/strong>, <em>In press<\/em>, <strong>2018<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\">Gottschalk, M. and <strong> Segura<\/strong>. Streptococcosis. <em>In<\/em>: Diseases of Swine. 11<sup>th<\/sup> edition, John Wiley &amp; Sons, Inc. <em>In press<\/em>, <strong>2018<\/strong>.<\/li>\n<li style=\"text-align: justify\"><strong>Segura, M.<\/strong>, N. Fittipaldi, C. Calzas and M. Gottschalk. Critical <em>Streptococcus suis<\/em> virulence factors: are they all really critical? <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28274524\"><strong>Trends in Microbiology <\/strong>25: 585-599, <strong>2017<\/strong>. Invited review<\/a>.<\/li>\n<li style=\"text-align: justify\">Lemire, P., T. Galbas, J. Thibodeau, and <strong> Segura<\/strong>. Natural Killer cell functions during the innate immune response to pathogenic streptococci. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28706510\"><strong>Frontiers in Microbiology<\/strong>, 8: e1196, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Auger, J.P., A. Santinon, D. Roy, K. Mossman, J. Xu, <strong> Segura<\/strong>, and M. Gottschalk. Type I interferon induced by <em>Streptococcus suis<\/em> serotype 2 is strain-dependent and may be beneficial for host survival. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28894449\"><strong>Frontiers in Immunology<\/strong>, 8: e1039, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\">Valanparambil, R.M., M. Tam, P. Gros, J.P. Auger, <strong> Segura<\/strong>, P. Gros, A. Jardim, T.G. Geary, K. Ozato, and M. Stevenson. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28968468\"><strong>Plos Pathogens<\/strong>, 13: e1006647 <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Martelet, L., S. Lacouture, G. Goyette-Desjardins, G. Beauchamp, C. Surprenant, M. Gottschalk, and <strong> Segura<\/strong>. Porcine dendritic cells as an <em>in vitro<\/em> model to assess the immunological behaviour of <em>Streptococcus suis<\/em> subunit vaccine formulations and the polarizing effect of adjuvants. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28327531\"><strong>Pathogens<\/strong>, 6: e13, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Calzas, C., M. Taillardet, I.S. Fourati, D. Roy, M. Gottschalk, H. Soudeyns, T. Defrance, and <strong> Segura<\/strong>. Evaluation of the immunomodulatory properties of <em>Streptococcus suis<\/em> and group B <em>Streptococcus <\/em>capsular polysaccharides on the humoral response. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28425925\"><strong>Pathogens<\/strong>, 6: e16, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Roy, D., T. Athey, J.P. Auger, G. Goyette-Desjardins, M.R. Van Calsteren, D. Takamatsu, M. Okura, S. Teatero, M. Alcorlo, J.A. Hermoso, <strong> Segura<\/strong>, M. Gottschalk and N. Fittipaldi. A single amino acid polymorphism in the glycosyltransferase CpsK defines four <em>Streptococcus suis<\/em> serotypes. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28642597\"><strong>Scientific Reports<\/strong>, 7: e4066, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Zheng, H., X. Qiu, D. Roy, <strong> Segura<\/strong>, P. Du, J. Xu, and M. Gottschalk. Genotyping and investigating capsular polysaccharide synthesis gene loci of non-serotypeable <em>Streptococcus suis<\/em> isolated from diseased pigs in Canada. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28219415\"><strong>Veterinary Research<\/strong>, 48: e10, <strong>2017<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong>Segura, M<\/strong>, C. Calzas, D. Grenier and M. Gottschalk. Initial steps of the pathogenesis of the infection caused by <em>Streptococcus suis<\/em>: fighting against non-specific defenses. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27539145\"><strong>FEBS<\/strong> <strong>Letters<\/strong>. 590: 3772-3799, <strong>2016<\/strong>. Invited review<\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Lecours, M.P., C. Letendre, D. Clarke, P. Lemire, T. Galbas, M.O. Benoit-Biancamano, J. Thibodeau, M. Gottschalk, and <strong> Segura<\/strong>. Immune-responsiveness of CD4+ T cells during <em>Streptococcus suis<\/em> serotype 2 infection. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27905502\"><strong>Scientific Reports, <\/strong>6: e38061, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Auger, J.P., N. Fittipaldi, M.O. Benoit-Biancamano, <strong> Segura<\/strong>, and M. Gottschalk. Virulence studies of different sequence types and geographical origins of <em>Streptococcus suis<\/em> serotype 2 in a mouse model of infection.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27409640\"><strong> Pathogens<\/strong>, 5: e48, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Roy, D., D. Grenier, <strong> Segura<\/strong>, A. Mathieu-Denoncourt, and M. Gottschalk. Recruitment of Factor H to the <em>Streptococcus suis<\/em> cell surface is multifactorial. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27399785\"><strong>Pathogens<\/strong>, 5: e47, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Vinogradov, E., G. Goyette-Desjardins, M. Okura, D. Takamatsu, M. Gottschalk, and <strong> Segura<\/strong>. Structure determination of <em>Streptococcus suis<\/em> serotype 9 capsular polysaccharide and assignment of functions of the <em>cps<\/em> locus genes involved in its biosynthesis. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27423880\"><strong>Carbohydrate Research<\/strong>, 433: 25-30, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Hathroubi, S., F. Beaudry, C. Provost, L. Martelet, <strong> Segura<\/strong>, C. Gagnon and M. Jacques. Impact of <em>Actinobacillus pleuropneumoniae <\/em>biofilm mode of growth on the lipid A structures and stimulation of immune cells. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=segura+Hathroubi\"><strong>Innate Immunity<\/strong>, 22: 353-362, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Goyette-Desjardins, G., C. Calzas, T. Shiao, A. Neubauer, J. Kempker, R. Roy, M. Gottschalk, and <strong> Segura<\/strong>. Protection against <em>Streptococcus suis<\/em> serotype 2 infection using a capsular polysaccharide glycoconjugate vaccine. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27113360\"><strong>Infection and Immunity<\/strong>, 84: 2059-2075, <\/a><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27113360\">2016<\/a>.<\/strong><\/li>\n<li style=\"text-align: justify\">Van Calsteren, M.R., G. Goyette-Desjardins, F. Gagnon, M. Okura, D. Takamatsu, R. Roy, M. Gottschalk, and <strong> Segura<\/strong>. Explaining the serological characteristics of <em>Streptococcus suis<\/em> serotypes 1 and 1\/2 from their capsular polysaccharide structure and biosynthesis. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26912653\"><strong>Journal of Biological Chemistry<\/strong>, 291: 8387-8398, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\">Auray, G., C. Lachance, Y. Wang, C. Gagnon, <strong> Segura<\/strong>, and M. Gottschalk. Transcriptional analysis of PRRSV-infected porcine dendritic cell response to <em>Streptococcus suis<\/em> infection reveals up-regulation of inflammatory-related genes expression. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27213692\"><strong>PLOS One<\/strong>, 11: e0156019, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Price, N., G. Goyette-Desjardins, H. Nothaft, E. Valguarnera, C. Szymanski, <strong> Segura<\/strong>, and M. Feldman. Glycoengineered outer membrane vesicles: A novel platform for bacterial vaccines. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27103188\"><strong>Scientific Reports<\/strong>, 6: e24931, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Teatero, S., P. Lemire, K. Dewar, J. Wasserscheid, C. Calzas, G. Mallo, A. Li, T. Athey, <strong> Segura<\/strong>, and N. Fittipaldi. Genomic recombination leading to decreased virulence of Group B <em>Streptococcus<\/em> in a mouse model of adult invasive disease. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27527222\"><strong>Pathogens<\/strong>, 5\u00a0: e54, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Clarke, D., C. Letendre, M.P. Lecours, P. Lemire, T. Galbas, J. Thibodeau, and <strong> Segura<\/strong>. Group B <em>Streptococcus<\/em> induces a robust IFN-g response by CD4+ T cells in an in vitro and in vivo model. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26989699\"><strong>Journal of Immunology Research<\/strong>, 2016: e5290604, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Aguiar, C., J. Therrien, P. Lemire, <strong> Segura<\/strong>, L. Smith, and C. Theoret. Differentiation of equine induced pluripotent stem cells into a keratinocyte lineage. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25781637\"><strong>Equine Veterinary Journal<\/strong>, 48: 338-345, <strong>2016<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong>Segura, M. <\/strong><em>Streptococcus suis<\/em> vaccines: candidate antigens and progress. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26468755\"><strong>Expert Review of Vaccines. <\/strong>14: 1587-608,<strong><\/strong> Invited review<\/a>.<\/li>\n<li style=\"text-align: justify\">Goyette-Desjardins, G., R. Roy and <strong> Segura<\/strong>. Murine whole-blood opsonophagocytosis assay to evaluate protection by antibodies raised against encapsulated extracellular bacteria. <em>In<\/em>: Carbohydrate-Based Vaccines &#8211; <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26169736\">Methods and Protocols Edition of &#8220;Methods in Molecular Biology&#8221; lab protocol series. B. Lepenies (Ed.) Springer, <strong>2015<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong> <\/strong>Calzas, C., P. Lemire, G. Auray, V. Gerdts, M. Gottschalk, and <strong> Segura<\/strong>. Antibody response specific to the capsular polysaccharide is impaired in <em>Streptococcus suis<\/em> serotype 2-infected animals. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25385801\"><strong>Infection and Immunity<\/strong>, 83: 441-453, <strong>2015<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong>Segura, M.<\/strong> <em>et al<\/em>. Latest developments on <em>Streptococcus suis<\/em>: an emerging zoonotic pathogen: part 2. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24957086\"><strong>Future Microbiology<\/strong> 9: 587-591, <strong>2014<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\"><strong>Segura, M.<\/strong> <em>et al<\/em>. Latest developments on <em>Streptococcus suis<\/em>: an emerging zoonotic pathogen: part 1. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24810343\"><strong>Future Microbiology<\/strong> 9: 441\u2013444, <strong>2014<\/strong><\/a>.<\/li>\n<li style=\"text-align: justify\">Goyette-Desjardins, G., J.-P. Auger, J. Xu, <strong> Segura<\/strong> and M. Gottschalk. <em>Streptococcus suis<\/em>, an important pig pathogen and emerging zoonotic agent &#8211; An update on the worldwide distribution based on serotyping and sequence typing. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26038745\"><strong>Emerging Microbes &amp; Infections<\/strong> 3: e45, <strong>2014<\/strong>. Invited review<\/a>.<\/li>\n<li style=\"text-align: justify\">Lemire, P. and <strong> Segura<\/strong>. The NOD2 receptor modulates cytokine response but does not alter the clinical outcome of Group B <em>Streptococcus<\/em>-infected mice. <a href=\"http:\/\/www.smartscitech.com\/index.php\/rci\/article\/view\/55\/pdf_4\"><strong>Receptors &amp; Clinical Investigation<\/strong> 2: 29-32, <strong>2014<\/strong>. Invited Research Highlight<\/a>.<\/li>\n<li style=\"text-align: justify\">Valanparambil, R<strong>.*<\/strong>, <strong> Segura*<\/strong>, M. Tam, A. Jardim, T. G. Geary, and M. M. Stevenson. Production and analysis of immunomodulatory excretory-secretory products from the mouse gastrointestinal nematode <em>Heligmosomoides polygyrus<\/em> bakeri. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25375989\"><strong>Nature Protocols<\/strong>, 9: 2740-2754, <strong>2014<\/strong><\/a>.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Biography Mariela Segura is an immunologist and Professor at the University of Montreal. She received her M.Sc. and Ph.D. from the Faculty of Medicine of the University of Montreal, where [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11407,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7864","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mariela Segura - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/microbiologie.umontreal.ca\/en\/professeurs-chercheurs\/mariela-segura\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mariela Segura - D\u00e9partement de microbiologie, infectiologie et immunologie - Universit\u00e9 de Montr\u00e9al\" \/>\n<meta property=\"og:description\" content=\"Biography Mariela Segura is an immunologist and Professor at the University of Montreal. 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