Séminaire aux membres CIRCA_ Dept microbiologie, infectiologie et immunologie, et Dept de Neuroscience.

Heure : 13h à 15h
Lieu : Université de Montréal_ Pavillon Paul-G-Desmarais. Local 1120
Adresse : 2960 Ch de la Tour, Montreal, QC H3T 1J4

8 JUILLET 2022, 13h00.

Pavillon Paul-G-Desmarais. Local 1120.

 

Manu Rangachari. PhD

Professeur titulaire, Département de médecine moléculaire, Université Laval

Chercheur régulier, axe Neurosciences, Centre de recherche du CHU de Québec.

 

Title. Adaptive immune parameters that regulate chronic central nervous system autoimmunity

Abstract. Multiple sclerosis (MS) is a chronic degenerative disease of the brain and spinal cord that is caused by an autoimmune attack against CNS tissues. Progressive MS is particularly refractory to current treatment modalities. In this seminar, I will discuss the role of biological sex in regulating disease outcomes in a model of progressive MS. I will also discuss the role of B cells in disease processes.

Key publications. PMID: 33691111, 34538129